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Live broadcast preview! ICEM 2022:advanced electron microscopy technology and Applications

From July 26 to 29, 2022, the instrument information network ( and the Chinese society of electron microscopy ( will jointly host the”eighth electronic microscopy network conference (ICEM 2022)”.

ICEM 2022 will invite well-known electronic microscopy experts in the industry to share wonderful reports online around the current research and application hotspots of electronic microscopy. There are six special sessions:electron microscopy technology and application progress, in-situ electron microscopy technology and application, application of electron microscopy technology in advanced materials, electron microscope experimental operation technology and experience sharing, application of electron microscopy technology in the field of materials, and application of electron microscopy technology in the field of life sciences. People in the industry are sincerely invited to sign up for the meeting.


Instrument information network, China electron microscope Society

Mode of participation

This conference is free to attend. Please click the official website of the conference for registration:

Or scan QR code to sign up

The following is a special preview of”advanced electron microscopy technology and application”

Note:the final schedule is subject to the official website of the conference

Special session 3:advanced electron microscopy technology and Application

(in the morning of July 27)

Special host:wanglihua, Professor of Beijing University of Technology


Report title



Electron tomography computed tomography based on laminated electron diffraction

Wang Peng (Professor of Nanjing University)


Research on cross scale lithium battery

Huang Jianyu (Professor of Yanshan University)


The latest development and application of Guoyi quantum electron microscope

Yin Xiangfei (Application Engineer of Guoyi quantum (Hefei) Technology Co., Ltd.)


The ESEM as In Situ Platform for the Study of Gas-Solid Interactions

Wang Zhujun (Shanghai University of science and Technology)


The latest technical progress of tescan double beam electron microscope

Yu Yan (tescan China Senior Application Engineer)


Technology breakthrough and application of spotlight technology navigator sem-100

Li Shuai (general manager of spotlight Technology (Beijing) Co., Ltd.)


In situ study on the atomic hierarchy mechanism of grain boundary plastic deformation

Wanglihua (Professor, Beijing University of Technology)


3D Electron Diffraction Methods for Crystal Structure Determination

Xuhongyi (researcher, Stockholm University, Sweden)

Guest profile and report summary

Wang Peng, Professor of Warwick University

[personal profile]

Wang Peng, professor and doctoral supervisor, has long been engaged in the research of micro characterization of structure and defects of functional materials and computer high-resolution imaging based on big data. In 2012, he returned to Nanjing University to teach and set up the Nanya atomic resolution electron microscope center. In the past five years, he has published 100 papers, including more than 40 papers by the first author/corresponding author, including 1 nature, 2 nature electronics, 3 nature communications, 1 Physical Review Letters, and 2 advanced materials. He has applied for and obtained a number of invention patents, including 3 international patent applications and 12 Chinese patents (10 of which are authorized). The h-index is 36. The chief scientist of”973″ of the Ministry of science and technology, presided over and participated in many international cooperation projects and other national, provincial and ministerial projects, and served as the director of the Chinese society of crystallography, electron microscopy, vacuum, etc.

Report title:Electron tomography computed tomography based on laminated electron diffraction

[Abstract]Combined with the big data of high-speed camera 4dstem diffraction, the”lensless” laminated electron diffraction technology based on computer algorithm is not limited by the inherent aberration of magnetic lens. It can obtain the two-dimensional to three-dimensional atomic structure information of ultra-high resolution, high phase contrast, light element sensitivity, low noise and low irradiation damage. It is expected to be applied to the high-resolution structural characterization of materials containing light elements and easily damaged by irradiation, It has potential and wide application prospects in the field of energy storage materials and structural biological macromolecular structure analysis.

Professor of Yanshan University/Xiangtan University Huang Jianyu

[personal profile]

Huang Jianyu,燕山大学和湘潭大学教授,博士生导师。博士毕业于中科院金属研究所;此后于日本国家无机材料研究所、日本大阪大学、美国洛斯阿拉莫斯国家实验室、波斯顿学院、桑迪亚国家实验室先后任职。一直以来以电子显微镜为主要研究手段,从事纳米力学与能源科学研究工作20多年。在电池研究领域取得了系列原创性的研究成果,建立了多种纳米力学和能源材料透射电镜-探针显微镜(TEM-SPM)的原位定量测量技术,在国际上率先制造出可在高真空度电镜中工作的锂电池,发明了在原子尺度上实时观察锂离子电池充放电过程的新技术,形成了原位纳米尺度电化学研究新领域,为锂离子电池研究提供了有效的技术手段。研究成果在《Science》、《Physical Review Letters》、《Nature Nanotechnology》、《Nature Communications》、《Nature Methods》、《PNAS》、《Nano Letters》等杂志上发表,共发表论文270余篇,h因子90,总引用次数近28000次,在各种专业学术会议上发表特邀报告100多次。

Report title:Research on cross scale lithium battery

[Abstract] The preparation of lithium batteries with high energy density, long cycle and high safety involves multi-scale structural optimization such as material preparation/characterization, electrode coating and battery assembly. Therefore, battery design is a multi-scale problem, and any problem in any link will lead to battery degradation and failure. Therefore, the development of cross scale lithium battery characterization technology is particularly important. In recent years, our research group has been engaged in the development of multi-scale lithium battery characterization technology. At the macro level, in-situ optical characterization technology was designed to successfully reveal the growth and transmission mechanism of lithium dendrites in solid-state batteries at the macro scale. At the mesoscopic level, the micro scale battery in FIB-SEM was developed, and the electrochemical mechanical coupling failure size effect of sulfide electrolyte was found. In the micro field, the microstructure and properties of nano materials are synchronously measured by combining transmission electron microscope and probe microscope (tem-stm). Using the tem-stm platform, the nano battery was constructed in the electric mirror for the first time, realizing the real-time in-situ observation of electrochemical reactions, and creating a new field of nano electrochemistry. Combined with micro electro mechanical heating system, atomic force microscope and spherical aberration correction environmental electron microscope, the tem-stm platform can be used to realize the in-situ electrochemical measurement under the condition of multi field coupling of temperature, pressure and atmosphere. This report will introduce the latest research results in the field of lithium battery research using in situ optics, FIB-SEM and tem-stm platforms. In the field of nano battery, it is found that lithium embedded in silicon leads to the size effect of pulverization. The mechanical properties of lithium and sodium dendrites were measured. It was found that the strength of nano lithium and sodium dendrites was more than 200 times higher than that of the corresponding bulk materials. The precise mechanical electrical coupling measurement of lithium dendrites is realized, and the mechanism of lithium dendrites penetrating solid electrolyte is revealed. The in-situ measurement of gas battery is realized by using spherical aberration correction environmental electron microscope. These basic researches provide a solid scientific foundation and technical path for the development of lithium batteries with high energy density, high power density and long cycle life.

Wang Zhujun, Professor of Shanghai University of science and technology

[personal profile]

He is mainly engaged in the development of new electron beam scanning imaging technology and its application research in surface science and catalytic science, and has more than 10 years of experience in the development of vacuum differential design and electron microscope scanning imaging technology. Based on the self-developed in-situ observation method, a series of innovative research achievements have been made in the fields of evolution behavior and mechanism of low dimensional nano materials on the surface of metal catalysts, surface and interface chemical oscillation, etc. It creates a real-time imaging characterization scheme with surface atomic level sensitivity in extreme environments (high temperature, near atmospheric pressure small molecules and corrosive atmosphere); The stacking order, interlayer force, growth and splicing behavior of two-dimensional materials during chemical vapor deposition are accurately measured, which can accurately control the structural properties of materials; The structure-activity relationship between product conversion and spatiotemporal patterns in the process of catalytic reaction on metal surface was revealed; Using scanning electron beam imaging as a bridge, a multi-scale in-situ observation method of surface interface is developed, and an attempt is made to bridge the three major gaps that have long plagued surface experimental science.

Report title:The ESEM as In Situ Platform for the Study of Gas-Solid Interactions

[Abstract] In order to understand the working principle of functional materials they should, at one point, be studied in their working state. In view of electron microscopy, atomic motion and chemical dynamics can be observed by in situ TEM. However, size constraints and the requirement of electron beam transparency impose substantial limitations with respect to dimension, complexity, and preparation of a specimen. Furthermore, atomistic details can only be resolved under conditions where atomic scale dynamics are slow compared to the temporal resolution of the detection system. In the case of gas-solid interactions, in situ TEM observations are therefore often performed at the reduced chemical potential of the reactive gas phase. Due to the strong focus on ultimate spatial resolution, the potential of environmental scanning electron microscopy (ESEM) as a flexible tool for in situ studies in the field of material science has recently been overlooked. In situ experiments performed in the ESEM can be used to complement localized information that is obtained by in situ TEM. Instead of atomistic details, it reveals the complexity of hierarchical multi-scale processes in which collective movements of a large number of atoms are involved. Thus, effects related to heat and mass transport are accessible. Compared to the TEM, the ESEM imposes far fewer restrictions with respect to available space and dimensions of the sample. This opens up the possibility to bridge the “materials gap” between simplified models- and complex real-world systems. Similarly, the focus on collective dynamics allow observations at the higher chemical potential of the reactive species and thus, a closing of the so-called “pressure gap”. Another important aspect is the reduced areal dose rate and lower kinetic energy of the beam electrons in ESEM. Contributions and extent of various beam-induced processes are different and, in most cases, less severe than in the TEM. Furthermore, the ESEM allows fast and efficient screening of the parameter field and facilitates more efficient use of the in situ TEM set-up. In order to obtain a unique platform for in situ studies of gas-solid interactions under a controlled atmosphere, we have equipped a commercial ESEM with a home-built gas-feeding station, a heating stage, and a mass spectrometer. For topography and 3D imaging of surface dynamics at temperatures of up to 1000 °C, a newly developed four-quadrant BSE detector was implemented. In addition, a detector for electron beam absorbed current (EBAC) was installed in order to complement the large-field detector with a signal that is independent of gas composition and pressure. It will be shown how the use of this instrument allows to study the emergence of catalytic function in the interplay between a gas phase and a metal catalyst. Dynamics of metal catalysts under redox conditions will be presented as well as the ability to study vapour-liquid-solid growth of 2D ribbon. Due to the high sensitivity of the SE signal, it is even possible to study metal catalysed chemical vapour deposition of graphene at 1000 °C. Finally, it will be demonstrated that contrast variations due to different molecular species on the surface of platinum during catalytic NO2 hydrogenation can be detected.

北京工业大学教授 王立华

[personal profile]

王立华,研究员,博士生导师,国家优秀青年基金获得者。2012年获得北京工业大学博士学位。2015-2017年,获得澳大利亚政府资助(Discovery Early Career Researcher Award),在昆士兰大学(全球排名前50)从事博士后研究工作。入选北京市卓越青年科学家、霍英东青年教师基金等人才计划。长期从事“原子尺度下材料力学行为的原位实验研究”,发表论文60余篇,其中包括自然子刊Nat. Commun. 4篇,Phys. Rev. Lett.1篇、Nano Lett. 4篇,Acta Mater.3篇,Appl. Phys. Lett.5篇等,被国际同行引用3000余次。主要成果获得2016年北京市科学技术奖一等奖,获北京市优博论文奖、郭可信优秀青年学子奖等。承担国家重点研发计划子课题、国家自然科学基金优秀青年基金、面上项目等多项国家及省部级项目。第一或通讯作者发表主要论文:1. Deli Kong et al., Nano Letters 19, 292 (2019).2. L. H. Wang et al., Physical Review Letters, 105, 135501 (2010)3. L. H. Wang et al., Nature Communications, 4, 2413 (2013)4. L. H. Wang et al., Nature Communications, 5, 4402 (2014)5. L. H. Wang et al., Nature Communications, 8, 2421 (2017)6. L. H. Wang et al., Nat. Commun. 11, 1167 (2020).7. L. H. Wang et al., Nano Letters, 17, 4733 (2017).8. L. H. Wang et al., Nano Letters. 11, 2382 (2011).9. L. H. Wang et al., ACS Nano, 2017, 11, 1250010. Shiduo Sun et al., ACS Nano, 13, 8708 (2019).

Report title:In situ study on the atomic hierarchy mechanism of grain boundary plastic deformation

[Abstract]  晶体变形过程中缺陷的形核及演化是组成这些缺陷的原子集体响应的动态过程。由于原有的原位实验技术分辨率长期局限于纳米尺度,导致人们对晶界变形的原子层次机理的认知强烈依赖于理论模型及计算机模拟,亟需原子层次原位实验证据澄清晶界塑性变形机制。本次报告主要介绍近年来团队在晶界变形机制研究的进展。主要是利用原创的实验技术,实现了多晶体系中晶界滑移、晶界原子扩散的原子层次动态观察。揭示出晶界滑移是通过晶界处原子相对滑移与原子短程扩散相互协调实现。研究晶界原子阵列合并消失、分裂出新原子阵列、原子迁移并插入晶体内部等多种新型的扩散机制。通过原位观察,发现晶界的产生及晶粒旋转的机制。

瑞典斯德哥尔摩大学研究员 徐弘毅

[personal profile]

After completing a Bachelor of Engineering (Mechatronics) degree at the University of Queensland (UQ), Hongyi went on to pursue a PhD degree in materials engineering, specialized in electron microscopy and semiconductor nano-materials. The Australian Government sponsored his PhD study through the Australian Postgraduate Award program. He obtained his PhD degree at UQ in Dec 2013, and received the Dean’s accommodation for academic excellence as well as the best thesis of the year award from the School of Mechanical and Mining Engineering. In Feb. 2014, Hongyi started his postdoc fellowship (Wenner-Gren Foundation postdoc award) in Prof. Xiaodong Zou’s group at Stockholm University. In 2015, he initiated the development of MicroED (3D electron diffraction technique for studying biomolecules) at Zou’s group. Hongyi became a principle investigator in 2018 to further develop and apply electron crystallography methods for studying structures of biomolecules. Recently, Hongyi and colleagues solved the first two previously unknown protein structures using MicroED. They have also shown that it is possible to reveal protein inhibitor binding by MicroED. Hongyi is now working as a researcher/principle investigator at Stockholm University.

Report title:3D Electron Diffraction Methods for Crystal Structure Determination

[Abstract] Knowing the 3D atomic structures of materials or biomolecules is crucial for understanding their functions. X-ray diffraction is currently the most important technique for determination of 3D atomic structures, but requires large crystals which are often difficult to obtain. Electrons, similar to X-rays and neutrons, are powerful source for diffraction experiments. Due to the strong interactions between electrons and matter, crystals that are considered as powder in X-ray crystallography can be treated as single crystals by 3D electron diffraction methods. This enables structure determination of materials and organic molecules from micron- to nanometer-sized 3D crystals that are too small for conventional X-ray diffraction. Furthermore, by taking the advantages of the unique properties of electron scattering, it is possible to determine the charge states of atoms/ions  and the absolute structure of chiral crystals. Over the past decades, a number of 3D ED methods have been developed for structure determination. At the early stages of 3D ED method development, tilting of the crystal was done manually, while diffraction patterns were collected on negative film. It could take years before sufficient data were obtained and processed in order to determine the crystal structure. The computerization of TEMs and the development of CCD detectors allowed software to be developed that can semi-automatically collect 3D ED data in less than an hour. Thanks to the recent advancement in CMOS and hybrid detector technology, it is now feasible to collect diffraction data in movie mode while continuously rotating the crystal (continuous rotation election diffraction, cRED, also known as MicroED in structural biology). Benefiting from these technological advances, structure determination can now be accomplished within a few hours. Recently, fully automated serial rotation electron diffraction data collection and processing has been realized by our group. By using 3D ED/MicroED methods, we have solved more than 200 novel crystal structures of small inorganic compounds (including zeolite, MOF, COF and minerals) and biomolecules  (pharmaceuticals, small organic molecules, peptides and proteins) in the past 7 years. Recently, we have solved two novel protein structures with 3D ED/MicroED and shown that it is feasible to use MicroED for structure based drug discovery. We aim to further improve these methods, develop new methods and more importantly spread them to labs around the world.

国仪量子(合肥)技术有限公司应用工程师 尹相斐

[personal profile]


Report title:The latest development and application of Guoyi quantum electron microscope

[Abstract] 国仪量子在显微成像领域有近20年的技术积累,于2018年发布了第一台商用扫描电镜,经过不断地优化升级,目前国仪量子的SEM3200型钨灯丝扫描电镜和SEM5000型场发射扫描电镜已具有出色的成像质量、丰富的扩展性、完善的自动功能和便捷的交互操作,能够帮助用户快速完成高分辨样品拍摄和显微分析,助力学术和工业用户在新能源、微电子、材料科学、生物医疗等领域的新材料研发和工艺优化。

TESCAN CHINA资深应用工程师 余妍

[personal profile]

材料学硕士,毕业于华侨大学。2019年加入TESCAN CHINA应用部,负责扫描电镜售前DEMO和售后技术服务工作。2011年开始负责FIB-SEM 售前技术交流、制样演示和售后技术服务工作。熟悉SEM和FIB在材料科学、半导体科学等领域的应用。

Report title:The latest technical progress of tescan double beam electron microscope

[Abstract] TESCAN双束电镜结合了高精度的FIB镜筒和超高分辨的SEM镜筒,同时拥有最佳离子束铣削能力和超高分辨率成像能力。镓离子FIB可以对10nm以下支撑的半导体器件进行高效、定点制备TEM样品;氙气等离子体FIB可以轻松应对宽达1mm的大面积截面加工。

聚束科技(北京)有限公司总经理 李帅

[personal profile]


Report title:Technology breakthrough and application of spotlight technology navigator sem-100

[Abstract] 聚束科技独立研发并拥有自主知识产权的NavigatorSEM-100高通量(场发射)扫描电子显微镜,通过对成像技术、运动平台、电路控制及智能算法的系统化创新设计,实现了全球最高通量成像,成像速度可达到传统电镜的数十倍以上。其全部采用直接电子探测器的技术方案,成功克服了传统SEM技术在速度、精度和样品损伤等方面的局限性,颠覆性地将扫描电镜从传统意义上的纳米“照相机”提升为纳米“摄像机”。